AKR1C2 anticorps

N° du produit ABIN7111467

Cet anticorps anti-AKR1C2 est un anticorps Lapin Polyclonal détectant AKR1C2 dans WB, ELISA et IF. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour AKR1C2 anticorps (ABIN7111467)

Antigène: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1C2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-AKR1C2 anticorps

Fonction: AKR1C2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: Aldo-keto reductase family 1 member C2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IF: 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur AKR1C2

Antigène: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Autre désignation: AKR1C2

Sujet:

Synonyms: Aldo-keto reductase family 1 member C2|3-alpha-HSD3|Chlordecone reductase homolog HAKRD|Dihydrodiol dehydrogenase 2 (DD-2, DD2)|Dihydrodiol dehydrogenase/bile acid-binding protein (DD/BABP)|Type III 3-alpha-hydroxysteroid dehydrogenase|AKR1C2|DDH2

Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.

Poids moléculaire: 37 kDa

UniProt: P52895

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process